Meganerv 300/Meganerv 1000 Special Precautions

Meganerv 300: Cyanocobalamin (Vitamin B12) should not be used to treat megaloblastic anemia of pregnancy. Administration of doses greater than 10 mcg of Vitamin B12 daily may produce a haematological response in patients with folate deficiency; indiscriminate use may mask the precise diagnosis. Cyanocobalamin or hydroxocobalamin should, if possible, not be given to patients with suspected vitamin B12 deficiency without first confirming the diagnosis.
Regular monitoring of the blood is advisable.
Meganerv 1000: The vitamins in Vitamins B1 + B6 + B12 (MEGANERV 1000) are non-toxic even in high doses and usually no adverse or after effects occur. However, sensitivity to Vitamin B1 may sometimes be encountered. Sensitivity may occur if administration at prolonged intervals is irregular, or if the initial dose is low and is suddenly increased.
Liver dysfunction also seems to predispose patients to hypersensitivity reactions. Nevertheless, it must be stressed that hypersensitivity to Vitamin B1 is very rare when given orally and is encountered more often only when given by intravenous injection.